About us

2bind offers tailor-made biophysical analytical services for protein / RNA targeted Drug Discovery, Antibody Research and Aptamer Development

Analytical services for Drug Discovery projects include:

  • Biophysical HTS assays (nanoDSF and MST)

  • Hit validation approaches (MST, nanoDSF)

  • HIt characterization (affinity, kinetics, thermodynamics and stoichiometry  to the target; nanoDSF, MST, BLI and ITC)

  • Binding assays in bioliquids (such as serum, plasma, cell lysate, saliva, urine).

  • HSA binding assays

  • competition assay

    Analytical services for antibody development projects include:

  • Buffer and detergent screening

  • Comparison of biosimilars to originators

  • ADC characterization

  • Long-term storage optimization assays

  • Forced degradation assays

    We have worked on over 600 projects with 6 of the top 10 global pharmaceutical companies, more than 60 SMEs and over 25 universities (e.g. MIT, Stanford). 2bind is the first CRO certified by NanoTemper Technologies for MST and nanoDSF.

Products and services

2bind offers customized biophysical analytical services in a fee-for-service business model for protein / RNA targeted Drug Discovery, Antibody Research and Aptamer Development projects.

2bind offers milestone based projects to Pharma, Biotech and Universities allowing the customer to have full control of the project, timelines and budget.

Various assay formats are available based on our core biophysical technologies MicroScale Thermophoresis (MST), nanoDSF, Biolayer Interferometry (BLI) and Isothermal Titration Calorimetry (ITC).

2bind´s portfolio of biophysical analytical services covers large parts of the early drug discovery process from Hit identification (HTS assays), Hit Validation and Hit Characterisation.

Furthermore, 2bind offers analytical assays for antibody and enzyme developers to optimize buffer/detergent conditions, long term storage, stress resistance and minimize aggregation tendencies of the protein of interest.

Address
2bind GmbH
Am BioPark 11
93053 Regensburg
Germany

Phone: +49 941 20000890
Internet: www.2bind.com
E-mail: Send message

Contact person

Dr. Thomas Schubert
CEO
E-mail: Send message

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