Usually, the optimization of the initial antibody candidates is necessary for the development of therapeutic antibodies. The YUMAB platform provides two in-vitro evolution technologies for the optimization of the antibody’s affinity, stability, specificity or selectivity: in-vitro evolution by YUlight shuffling and in-vitro evolution by mutagenesis.

Additionally, in-silico analysis can be applied to identify and optimize antibodies with the best developability score.