Functional Labels with gas barrier properties from Schreiner MediPharm can significantly reduce oxygen diffusion in COC syringes due to their special material selection and design. Several variants are available, for instance a Gas-Protect-Label covering the syringe barrel and a Syringe-Closure-Wrap label with an additional barrier function that wraps around the syringe barrel and the cap and is sealed at the upper end. Syringe-Closure-Wrap additionally offers an integrated first-opening indication to ensure product integrity from production till final use.